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Abstract
To investigate the multimodal ultrasonography (US) features of extramedullary plasmacytomas (EMPs) in patientswith multiple myeloma (MM). Nine patients with MM who were diagnosed EMPs and underwentmultimodal ultrasonography were enrolled in this study. Clinical information and multimodal US results were retrospectivelyanalyzed. The multimodal US with a standardized sonographic protocol including US, color Doppler flow imaging (CDFI),microvascular US, ultrasound elastography (UE) and contrast-enhanced ultrasound (CEUS) was performed on the enrolledpatients. This study included both males (4 of 9) and females (5 of 9), with ages ranging from 48 to 72 years. Thenine lesions were located in the skin/muscle (7 of 9) and pleura (2 of 9). On US images, all lesions showed inhomogeneoussolid hypoechogenicity without calcification. Vascularity was abundant (hypervascularization). CEUS images confirmed thisvascular pattern (9 of 9) and presented hyperenhancement with enlarged range. On elastographic images, the lesions presentedwith high elastic score (3-4). An inhomogeneous hypoechoic soft tissue or visceral mass occurring in MM withincreased vascularity, low elasticity, and hyperenhancement along with enlarged range can indicate the diagnosis of EMP onmultimodal US images.
Published Version
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