Abstract
Modern medicine requires to combine the imaging and therapy tools in one object. Two types of nanostructured shells were elaborated. The first type of shell that exhibited the highest photoacoustic and fluorescent signals have utilized a combination of gold nanorods and indocyanine green dispersed in the matrix of biodegradable polymers. The second type based on composite indocyanine green/polymer using a self-quenching effect has been successfully prepared and characterized by fluorescent and optoacoustic tomographies. Optimal compositions and structures of nanostructured shells from point of view of photoacoustic and fluorescent signal intensities required for detection of nanostructured shell in vivo were found.
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