Abstract
The desirable physical and physiochemical properties of clay minerals have led them to play a substantial role in pharmaceutical formulations. Clay minerals like kaolin, smectite and palygorskite-sepiolite are among the world's most valuable industrial minerals and of considerable importance. The elemental features of clay minerals which caused them to be used in pharmaceutical formulations are high specific area, sorption capacity, favorable rheological properties, chemical inertness, swelling capacity, reactivity to acids and inconsiderable toxicity. Of course, these are highly cost effectual. This special report on clay minerals provides a bird's eye view of the chemical composition and structure of these minerals and their influence on the release properties of active medicinal agents. Endeavor has been made to rope in myriad applications depicting the wide acceptability of these clay minerals.
Highlights
Multifaceted role of clay minerals in pharmaceuticalsThe desirable physical and physiochemical properties of clay minerals have led them to play a substantial role in pharmaceutical formulations
The enormous surface area, surface chemistry and surface charge impart significant and unique physical properties to the clay minerals, owing to which these possess tremendous scope to be utilized as therapeutic, cosmetics, functional, inert and bulk agents
Clay minerals serve as lubricants, desiccants, disintegrants, diluents, binders, pigments and opacifiers
Summary
The desirable physical and physiochemical properties of clay minerals have led them to play a substantial role in pharmaceutical formulations. The elemental features of clay minerals which caused them to be used in pharmaceutical formulations are high specific area, sorption capacity, favorable rheological properties, chemical inertness, swelling capacity, reactivity to acids and inconsiderable toxicity. The minerals employed primarily are oxides, carbonates, sulphates, chlorides, hydroxides, sulphides, phosphates, nitrates, borates and phyllosilicates These are widely put into use owing to their unique features. Clay minerals are widely used in in broader terms, clay minerals practically the pharmaceutical industry as lubricants, involve minerals of the above-cited particles desiccants, disintegrants, diluents, binders, size These are essentially composed of sil- pigments and opacifiers.
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