Abstract
This was the first Indian multicenter study at six specialty hospitals, to assess the real-life usage of the vaginal ring in daily clinical practice. This open-label, prospective, single-arm, nonrandomized, interventional study enrolled 252 women aged >18years, seeking contraception with no contraindications to the use of combined hormonal contraceptive. Women were provided the ring with a monthly follow-up schedule for three cycles. Cycle control, acceptability, tolerability, and safety assessments were recorded at each visit. Regular menstrual bleeding was reported by 76.2% (192/252) at baseline. In study completers, regular bleeding was seen in 94.1% (192/204), 97.5% (199/204), and 98% (200/204) in the 1st, the 2nd, and the 3rd cycles, respectively. Most (94.2% [195/207]) women were very satisfied or satisfied with the ring, and 93.2% (193/207) would recommend it to others. No pregnancies or serious adverse events were reported. The study demonstrated that NuvaRing(®) is a highly effective contraceptive method with an excellent cycle control. It is well tolerated and accepted by Indian women.
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