Muhtemelen Atlanılan Bir Tanı: Rubeola Lenfadeniti, Yeniden Alarm Veren Bir Salgın

Abstract

Because Rubeola (measles) infection is not observed in our country after eradication and is especially on the agenda again after migrations, pathologists may find it challenging to histopathologically recognize cases of Rubeola lymphadenitis and establish an accurate diagnosis. Here we describe the histopathological features of a rare Rubeola case. A 15-year-old Syrian migrant male patient was admitted with a complaint of lymph node swelling in the postauricular region for 2 months. Lymph node excision was performed with a preliminary diagnosis of lymphoma. The excised lymph node was subjected to a routine pathological examination in our clinic. Histopathological examination revealed that the basic structure was preserved under the thick fibrous capsule in the lymph node. Warthin-Finkeldey-type giant cells attracted attention in the interfollicular areas. The appearance compatible with lymphoproliferative neoplasia was not detected. The relevant clinic was informed that there were histological signs of Rubeola lymphadenitis upon detection of Rubeola IgM positivity in the examination, the case was evaluated as Rubeola infection. Rubeola was a common deadly infectious disease in the past century before the vaccine was developed. Today, there has been an epidemic again due to vaccine hesitancy, migration, and sociocultural conditions. Because it is exceptionally rare, we hope that the case we present will provide insights to pathologists for recognizing cases of Rubeola lymphadenitis and making precise diagnoses.