Abstract
Mammalian target of rapamycin (mTOR) signaling pathway is in the central part of the growth regulating that has received increasing concern. It is centrally involved in control of cell growth, proliferation, differentiation and cell cycle regulation. Complicated and the dysregulation of mTOR pathway is recognized to be associated with lots of tumors. Recent studies have found that mTOR signaling pathway express excessively in cervical cancer,which indicates that the occurrence and development of cervical cancer has close inner link with mTOR signaling pathway. It also provides the basis for searching the specific targeted therapy drugs to block this pathway, but the specific mechanism still needs further study. In this treatise,the author summarizes the development of researches on the composition, function and regulation of mTOR signaling pathway and its correlation with the development of cervical carcinoma. Key words: mTOR signaling pathway; tumor; cervical cancer; targeted therapy
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