Abstract
Background: The impact of different extracorporeal circulation (ECC) scenarios on arterial blood flow profiles remains yet unclear. Presently, computational fluid dynamics (CFD) allow for the simulation of blood flow profiles, local flow velocities, emergence of turbulences, and wall shear stress (WSS). However, the underlying simulation algorithms require validation by in vivo measurements. Therefore, we used our previously published miniaturized MRI-compatible rabbit ECC model to demonstrate blood flow profiles, wall shear stress and turbulences in dependency on different ECC scenarios in an MRI scanner, aiming at the validation and optimization of numerical blood flow simulation algorithms.
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