Abstract

Balo’s concentric sclerosis (BCS) is rare demyelinating disease considered to be variant of multiple sclerosis. The initial terminology for this entity was leuko-encephalitis periaxialis concentrica, which is based on its early definition of a disease in the course of which the white matter of the brain is destroyed in concentric layers in manner that leaves the axis cylinders intact. The most common clinical features are headache, aphasia, cognitive or behavioural dysfunction and/or seizures. CSF studies often reveal mononuclear inflammatory reaction and occasionally monoclonal bands. 2 The typical MR imaging changes associated with BCS consist of concentric rings or whorled appearance on T2-weighted and contrast-enhanced T1-weighted images. Differentiating BCS from multiple sclerosis or neoplasm can be difficult clinically, but MR imaging findings noted in this case may be pathognomonic. In this case report we present case of balo's concentric sclerosis diagnosed on MRI.

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