MP48-06 GENDER IMPACT ON BLADDER-RELATED OUTCOMES AND QUALITY OF LIFE AFTER PARAPLEGIC SPINAL CORD INJURY

Abstract

You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Neurogenic Voiding Dysfunction (MP48)1 Apr 2020MP48-06 GENDER IMPACT ON BLADDER-RELATED OUTCOMES AND QUALITY OF LIFE AFTER PARAPLEGIC SPINAL CORD INJURY Sara Lenherr*, Jennifer S. Herrick, Sean P Elliott, Angela P. Presson, Odinachi Moghalu, John T Stoffel, Blayne Welk, and Jeremy B Myers Sara Lenherr*Sara Lenherr* More articles by this author , Jennifer S. HerrickJennifer S. Herrick More articles by this author , Sean P Elliott Sean P Elliott More articles by this author , Angela P. PressonAngela P. Presson More articles by this author , Odinachi MoghaluOdinachi Moghalu More articles by this author , John T StoffelJohn T Stoffel More articles by this author , Blayne WelkBlayne Welk More articles by this author , and Jeremy B MyersJeremy B Myers More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000000903.06AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Females with spinal cord injury (SCI) have been collectively analyzed along with males with SCI, despite the fact that women have fundamentally different genitourinary anatomy. We hypothesized that women have different patient reported outcomes and quality of life (QoL) related to their neurogenic bladder dysfunction. METHODS: The Neurogenic Bladder Research Group (NBRG) SCI Registry is a multicenter prospective observational study designed to assess bladder−related symptoms and QoL after SCI. Outcomes included the Neurogenic Bladder Symptom Score (NBSS) total score and a global satisfaction with urinary function question (NBSS-QoL). Bladder management was categorized as: clean intermittent catheterization without prior bladder surgery (CIC), indwelling catheter (urethral or suprapubic), surgical (bladder augmentation, catheterizable channel, urinary diversion), or voiding (condom catheter, involuntary leaking, volitional). Multivariate linear regression analysis was conducted controlling for age, obesity, years since injury, chronic pain, UTI burden (>4 per year), severe bowel dysfunction, SCI-QoL bladder management difficulties and SCI-FI fine motor score. RESULTS: 1479 participants (894 male and 585 female) were identified. Mean age of 44 ± 13 years and mean 16 ± 12 years since SCI. SCI level was: 57% paraplegia & 43% tetraplegia. Among paraplegic participants (470 male, 373 female), females who had a bladder surgery (n=71) reported a better total NBSS score (adjusted difference (AD) -3.35, 95% CI -5.85 to -0.85, p=0.009) and better bladder-related QoL (AD -0.71, 95% CI -1.03 to -0.39, p<0.0001) compared to those using intermittent catheterization (n=198). In contrast, males who had surgery (n=30) did not have a statistically different total NBSS total score (AD 1.77, 95% CI -2.01 to 5.55, p=0.36) compared to those using intermittent catheterization (n=327) but bladder-related QoL was improved (AD -0.59, 95% CI -1.11 to -0.07, p=0.03). CONCLUSIONS: There are differences in neurogenic bladder symptoms based on gender after spinal cord injury. Women with paraplegia experience worse bladder-related symptoms and have more opportunity for improvement with surgery. Educational efforts to improve bladder-related outcomes should be tailored to address gender-specific concerns. Source of Funding: PCORI CER14092138 © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 203Issue Supplement 4April 2020Page: e696-e696 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Sara Lenherr* More articles by this author Jennifer S. Herrick More articles by this author Sean P Elliott More articles by this author Angela P. Presson More articles by this author Odinachi Moghalu More articles by this author John T Stoffel More articles by this author Blayne Welk More articles by this author Jeremy B Myers More articles by this author Expand All Advertisement PDF downloadLoading ...