MP35-09 PHYSICAL ACTIVITY AS A RISK FACTOR FOR LOWER URINARY TRACT SYMPTOMS DIAGNOSIS IN PATIENTS WITH BENIGN PROSTATIC ENLARGEMENT: A PROSPECTIVE MULTICENTER COHORT ANALYSIS

Abstract

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Epidemiology & Evaluation1 Apr 2016MP35-09 PHYSICAL ACTIVITY AS A RISK FACTOR FOR LOWER URINARY TRACT SYMPTOMS DIAGNOSIS IN PATIENTS WITH BENIGN PROSTATIC ENLARGEMENT: A PROSPECTIVE MULTICENTER COHORT ANALYSIS Cosimo De Nunzio, L. Cindolo, F. Cancrini, M. Gacci, F. Pellegrini, P. Castellan, R. Lombardo, F. Presicce, A. Brassetti, M. Bellangino, G. Tema, L. Schips, A. Sica, and A. Tubaro Cosimo De NunzioCosimo De Nunzio More articles by this author , L. CindoloL. Cindolo More articles by this author , F. CancriniF. Cancrini More articles by this author , M. GacciM. Gacci More articles by this author , F. PellegriniF. Pellegrini More articles by this author , P. CastellanP. Castellan More articles by this author , R. LombardoR. Lombardo More articles by this author , F. PresicceF. Presicce More articles by this author , A. BrassettiA. Brassetti More articles by this author , M. BellanginoM. Bellangino More articles by this author , G. TemaG. Tema More articles by this author , L. SchipsL. Schips More articles by this author , A. SicaA. Sica More articles by this author , and A. TubaroA. Tubaro More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.1601AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Aim of our study was to assess the association between physical activity, evaluated by the Physical activity scale for elderly (PASE) questionnaire and lower urinary tract symptoms (LUTS) in patients with benign prostatic enlargement. METHODS From 2009 onward, a consecutive series of patients with LUTS-BPE were enrolled. Patients were evaluated using the International Prostate Symptom Score (IPSS) and ultrasonographic prostate volume. Body mass index, waist circumference and blood pressure were measured. Blood samples were collected for prostate-specific antigen levels. Physical activity was evaluated with the PASE questionnaire, consisting of 12 questions regarding frequency and duration of leisure activity and recently used to evaluate physical activity in patients with prostatic disorders. The risk of detecting LUTS (IPSS >7) was evaluated using the logistic regression analysis. RESULTS 617 patients were enrolled in two centers (Rome, Vasto, Italy) with a median age of 67 years (IQR 61/73) and PSA of 6 ng/ml (IQR 4/8). Median BMI was 26.4 kg/m2 (IQR: 24.5/28.7); 72/617 (12%) patients were obese. Median waist circumference was 101 cm (IQR: 96/108), median PASE score was 118 (IQR73/169), and median IPSS was 9 (IQR 5/15). Overall 189/617 (30%) patients presented with moderate/severe LUTS. Patients with moderate/severe LUTS presented a higher PASE score (111 IQR 69/160 vs 125 IQR 83/180; p= 0.016). On multivariate analysis, PASE score (OR: 1.003 per unit, 95%CI: 1.001 – 1.006; p= 0.037) and TRUS volume (OR=1.009 per ml, 1.001-1.017; p=0.025) were independent risk factors for LUTS severity. CONCLUSIONS In our multicentre study a reduced physical activity, assessed using the PASE questionnaire, is associated with an increased risk of moderate severe LUTS. Although these results should be confirmed, and the pathophysiology is yet to be completely understood, assessment of patients physical activity is suggested in the evaluation of patients with LUTS. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e483 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Cosimo De Nunzio More articles by this author L. Cindolo More articles by this author F. Cancrini More articles by this author M. Gacci More articles by this author F. Pellegrini More articles by this author P. Castellan More articles by this author R. Lombardo More articles by this author F. Presicce More articles by this author A. Brassetti More articles by this author M. Bellangino More articles by this author G. Tema More articles by this author L. Schips More articles by this author A. Sica More articles by this author A. Tubaro More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...