MP28-06 THE ASSOCIATION OF ANXIETY IN YOUNGER VS OLDER MEN WITH BENIGN PROSTATIC HYPERPLASIA

Abstract

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Epidemiology & Evaluation (MP28)1 Sep 2021MP28-06 THE ASSOCIATION OF ANXIETY IN YOUNGER VS OLDER MEN WITH BENIGN PROSTATIC HYPERPLASIA Kevin A. George, Sarah S. Makhani, Adam Nolte, George Wayne, and Alan Nieder Kevin A. GeorgeKevin A. George More articles by this author , Sarah S. MakhaniSarah S. Makhani More articles by this author , Adam NolteAdam Nolte More articles by this author , George WayneGeorge Wayne More articles by this author , and Alan NiederAlan Nieder More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002025.06AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Men with benign prostatic hyperplasia (BPH) commonly have lower urinary tract symptoms (LUTS), including frequency, urgency, and hesitancy, which cause significant distress. Recent evidence has shown a bidirectional relationship between LUTS and mental health. This study aims to assess the association of anxiety in younger men with BPH as compared to older men. METHODS: Data were obtained from the 2016 National Inpatient Sample (NIS). NIS is the largest all-payer inpatient database for United States hospitalizations. For analysis, we selected a subset of this sample, which included male hospitalizations over the age of 18 with BPH. Men between the ages of 18-64 were compared with men 65 years or older. Univariate and multivariate logistic regressions were used to determine the association between age and anxiety, reporting odds ratios and their corresponding 95% confidence intervals. Multivariate analysis controlled for race, major comorbidities (diabetes, hypertension, coronary artery disease), hospital location, insurance status, median household income, and overall disease burden. Sampling weights were used to generate nationally representative estimates. RESULTS: Among the 1,501,714 men with BPH, 142,959 (9.5%) had comorbid anxiety while 1,358,754 (90.5%) did not. Of the 262,124 men 18-64 years old, 37,725 (14.4%) had anxiety, while of the remaining 1,239,589 men 65+ years old, 105,234 (8.5%) had anxiety (p <0.001). Accordingly, upon multivariate analysis, the odds of anxiety were 1.5 times greater in the younger cohort as compared to the older cohort (adjusted OR=0.55, p <0.001, 95% CI [0.54, 0.57]). Additionally, multivariate analysis revealed significantly greater odds of anxiety in Black, Hispanic, and Asian men, men with Medicare or Medicaid, men in the first, second, and third quartiles of median household income, and men with hypertension and diabetes mellitus. CONCLUSIONS: This study shows a higher prevalence of anxiety in younger individuals (18-64 yrs) with BPH as compared to older individuals (65+ yrs). To our knowledge, this is the first study to examine the association between anxiety and patient age in individuals with BPH in a nationally representative sample. These findings may have implications for the biopsychosocial approach to the management of BPH. Source of Funding: None © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e482-e483 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Kevin A. George More articles by this author Sarah S. Makhani More articles by this author Adam Nolte More articles by this author George Wayne More articles by this author Alan Nieder More articles by this author Expand All Advertisement Loading ...