Abstract

Prostate cancer is the second leading cause of cancer mortality among men in the US. To the authors' knowledge, there was no improved, second-line therapy for metastatic hormone refractory prostate cancer (HRPC). Recent data suggest that docetaxel-based chemotherapy has been effective in HRPC. Combination chemotherapy using carboplatin and weekly docetaxel was examined in Japanese patients with metastatic HRPC.

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