Morphological spectrum of soft tissue tumors in a tertiary care hospital affiliated with a teaching institute: A 4 years retrospective study

Abstract

Aims and Objectives: 1) To study the morphological spectrum of soft tissue tumors in detail on the basis of both histopathological features and recent WHO classification and 2) To study the relative frequencies of Benign, Intermediate and Malignant tumors along with their locations, age groups of presentation and gender ratio. Materials and Methods: The present 4 years retrospective study was conducted at the department of Pathology, GMERS Medical College-Junagadh from January 2015 to December 2018. It includes 105 cases of soft tissue tumors that presented and diagnosed at our institute on both clinical and pathological basis. Results: Out of 105 cases, 101 (96.19%) were benign, only one (0.95%) was intermediate & 3 (2.86%) were malignant in nature. The commonest age group was 41-50 years & M: F ratio was 1.56:1. Among benign tumors, adipocytic tumors constituted majority of the cases (78.22%) followed by vascular tumors (7.92%). Both upper & lower extremities were found to be the commonest location for such tumors. Conclusion: Soft tissue tumors are diagnosed on the basis of gross & light microscopic features in majority of the cases. However, in certain cases of malignancies or sarcomas, ancillary techniques like special histochemical staining & IHC become quite helpful in diagnosis. Keywords: Peripheral Neuroblastic tumors, Neuroblastoma, Ganglioneuroblastoma, Ganglioneuroma, Immunohistochemistry.