Morphological monitoring indexes in anterior segment with primary acute angle closure glaucoma

Abstract

To investigate morphological monitoring indexes of anterior segment in AACG. Case-controlled study was conducted in the following groups: 55 eyes of 55 patients with unilateral AACG in first attack, 60 eyes of 60 cases with shallow anterior chamber, and 60 eyes of 60 cases with normal individuals. Images of anterior chamber angle in each group were collected by OCT. Using software of Photoshop, the opening degree of anterior chamber angle was quantified. Anterior chamber depth (ACD), lens thickness (LT), lens position (LP), and chamber crowding rate (CCR) were measured by A-ultrasound. Anterior segment biometric parameters among the three groups were compared using one-way ANOVA test. LT, LP, and CCR were significantly (LT: F = 27.73, LP: F = 47.33, CCR: F = 79.22; P < 0.05) different between AACG, narrow angle and normal group in age group ranged from 50 to 59 [LT: (5.72 ± 0.22) mm, (5.57 ± 0.28) mm, (4.55 ± 0.36) mm, LP: (4.33 ± 0.24) mm, (4.63 ± 0.20) mm, (5.71 ± 0.34) mm, and CCR: 3.28 ± 0.16, 2.64 ± 0.19, 1.70 ± 0.10, respectively] and significantly different (LT: F = 22.51, LP: F = 56.67, CCR: F = 74.84; P < 0.05) in age group ranged from 60 to 69 [LT: (5.81 ± 0.37) mm, (5.72 ± 0.41) mm, (4.98 ± 0.59) mm, LP: (4.26 ± 0.18) mm, (4.51 ± 0.14) mm, (5.62 ± 0.19) mm and CCR: 3.39 ± 0.35, 2.74 ± 0.37, 1.86 ± 0.36, respectively]. However, in age group ranged above 70 group, LP and CCR (LP: F = 23.09, CCR: F = 60.08; P < 0.05) were significantly changed [LP: (4.25 ± 0.30) mm, (4.46 ± 0.22) mm, (5.49 ± 0.23) mm, CCR: 3.48 ± 0.21, 2.85 ± 0.30, 2.03 ± 0.17, respectively], but not LT [(5.85 ± 0.27) mm, (5.74 ± 0.21) mm, (5.43 ± 0.36) mm] (F = 8.29, P > 0.05). The study results indicate that LT, LP and CCR, are useful indicators to observe the anterior chamber status in AACG by using Stratus OCT-3.