Modified mesoporous aluminophosphate as an efficient solid acid catalyst for the synthesis of novel O- and N-acetylated compounds: solvent free condition

Abstract

Solid acids such as amorphous aluminophosphates (AlP) modified with different transition metals (Fe/Mo/W) were synthesized by either precipitation or co-precipitation methods. These solid acids were characterized by BET, NH3-TPD, PXRD and FT-IR techniques. The catalytic activity of these solid acids was evaluated in the synthesis of novel O- and N-acetylated compounds of various substituted alcohols, phenols, pyridine alcohols, furan alcohols, aryl alcohols and amines under solvent free conditions with acetic anhydride as an acetylating agent. The reaction conditions were optimized by varying the catalyst, molar ratio of the reactants, reaction temperature and amount of the solid acid catalyst. Among the solid acids, FeAlP consisting of 0.025 mol% Fe showed good catalytic activity in the acetylation reaction and produces high yield of acetylated products. In addition, the catalysts can also be reused in acetylation at least for 4 reaction cycles without significance loss of catalytic activity.