Modification of the cotton woven fabrics with Tancho® for using on the diabetic foot symptom

Abstract

Diabetes is a chronic disease that is widely spread in this time. Diabetic foot is one of the most common symptoms, it starts when the dryness emerge after that the cracks appear on the back or outcrops of the foot. The primary treatment for these symptoms is considered the best choice to prevent diabetic foot diseases. The aim of this study is using treated fabric with Tancho® (based on olive oil) to give the cracked or pre-ulcer foot the sufficient hydration for skin cells during the rest periods to heal. The study was based on using 100% cotton woven fabrics with three structures that are treated with Tancho® petroleum jelly as emulsion using two techniques; Pad/Batch and Pad/Dry/Cure methods, to compare between them in the improvement of fabric for healing. Weight and thickness were conducted to evaluate the fabric functional performance before and after treatment with Tancho®. The antimicrobial activity was done for samples to determine the biological property. Roughness, SEM and TEM were done to study the morphological surface of samples produced. Finally, the best samples performances as a result from radar chart analysis were applied in vivo for rats, to determine the efficiency of the treated samples through clinical observation and histopathological changes. The results of the produced samples that weaved by three different structures and treated with Pad/Batch method were increased of the stimulation of skin cells to heal after surgical either in case of use for surface skin scratches or as scaffold for skin layers.