Abstract
In this study, thin calcium phosphate (Ca-P) coatings were deposited on zirconia substrates by radiofrequency (RF) magnetron sputtering using different calcium phosphate targets (calcium phosphate tribasic (CPT), hydroxyapatite (HA), calcium phosphate monobasic, calcium phosphate dibasic dehydrate (DCPD) and calcium pyrophosphate (CPP) powders). The sputtering of calcium phosphate monobasic and DCPD powders was carried out without an inert gas in the self-sustaining plasma mode. The physico-chemical, mechanical and biological properties of the coatings were investigated. Cell adhesion on the coatings was examined using mesenchymal stem cells (MSCs). The CPT coating exhibited the best cell adherence among all the samples, including the uncoated zirconia substrate. The cells were spread uniformly over the surfaces of all samples.
Highlights
In recent years, there has been a shift from amputation to treatment with endoprosthetics, which is driven by the desire to improve surgical techniques
This paper provides a comparative study of coatings deposited by the radiofrequency (RF) magnetron sputtering of different calcium phosphate (Ca-P) powders on zirconia substrates
Ca-P powders using RF magnetron sputtering led to changes in its morphology
Summary
There has been a shift from amputation to treatment with endoprosthetics, which is driven by the desire to improve surgical techniques. The number of patients with surgically implanted artificial devices in bone and joint tissues is currently increasing [1,2]. These implants allow people to lead more normal lives without feeling restricted in movement. Ceramics are used to construct prostheses or their parts to manufacture medical instruments, as membranes for the separation and purification of biological fluids, and to produce porous elements for dosed drug administration [3,4,5]. As biologically inert and electrolytically passive materials, ceramics do not conduct electric current. Ceramics show good integration ability with bone tissue, making them advantageous in comparison with metal implants [6,7,8,9,10,11]
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