Abstract
More than 20% of people worldwide suffer from allergic diseases. The high prevalence and wide range of provocative factors, which are increasing daily, complicate the diagnostic search. On the one hand, this leads to inadequately extensive dietary and lifestyle restrictions that reduce the quality of life for patients; on the other hand, it results in the failure to identify life-threatening allergens. The discovery of immunoglobulin E over 60 years ago initiated the search for specific biomarkers to etermine the causes of allergic diseases. Traditional methods of allergen diagnostics have several limitations that hinder the search for potential allergic disease triggers. The article discusses modern laboratory approaches to multicomponent molecular allergen diagnostics, describes its differences from traditional diagnostic methods, and analyzes the advantages, prospects, limitations, and shortcomings of this method. It also presents a comparative characterization of the test systems available today. The article presents four clinical cases that demonstrate the capabilities of the multicomponent ALEX 2 test system in diagnostics, choice of therapy tactics, and in forming further personalized recommendations for patients suffering from various allergic diseases.
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