Abstract

The study of cognitive impairments (CI) began with a more severe form- dementia, which is usually the result of a long-running pathological process. It is preceded by non-demented cognitive disorders (including mild cognitive impairment syndrome — MCI), whose early detection increases the potential for therapeutic effects and even prevention of disadaptation as a result of dementia. The article reviews current publications on the problem of MCI. Special attention is paid to the diagnosis and treatment of this clinically heterogeneous syndrome. Historical issues of MCI studying are considered, modern principles of its classification and diagnostic criteria are given, and the main aspects of patient management are described. The results of a number of russian and international studies of MCI syndrome are described, including a comparison of these data among themselves.

Highlights

  • It is preceded by non-demented cognitive disorders

  • whose early detection increases the potential for therapeutic effects

  • Special attention is paid to the diagnosis and treatment

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Summary

Introduction

В настоящее время принято считать, что оригинальные диагностические критерии описывают лишь один подтип синдрома УКР, а именно монофункциональный амнестический подтип. В 2005 году были предложены следующие модифицированные диагностические критерии синдрома УКР Объективные проявления нарушений памяти и/или других когнитивных функций, полученные при помощи нейропсихологических тестов; 2. Когнитивные нарушения не лишают пациента независимости в повседневной деятельности (в том числе в комплексных ее видах, например при осуществлении финансовых операций или приеме лекарств).

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