Abstract

Aims: Alcohol andmarijuana (cannabis) are the twomost commonly used psychoactive drugs and each appears to have its own unique sexual effects on users. With marijuana use increasing in the United States, along with more liberal state-level policies, it is important to examine and compare sexual effects and sexual risk behavior associated with these drugs in order to inform prevention of HIV, other sexually transmitted infections and unplanned pregnancy. Methods: We conducted semi-structured interviews with 24 racially and ethnically diverse adults in New York City (mean age=27.4, SD=5.8). To be eligible, subjects must have (1) been between ages 18–35, (2) had sex while high on marijuana in the last 12 months, (3) had sex while not high on marijuana in the last 12 months; and (4) must not have used any other illicit drug in the last 12 months. All subjects self-identified as heterosexual and HIV-negative, and 50% were female. Results: Thematic analysis yielded various themes. Many subjects described differences between the two drugs with regard to interactions and contexts in use before sex, partner choice, perceived attractiveness of self and others, disinhibition, adverse sexual effects and sexual dysfunction, and dose effects. Differences were also commonly described regarding libido, length and intensity of sex and orgasm, specific sexual behaviors (including risk behavior), and feelings such as regret after sex. Compared to marijuana, alcohol was more likely to be associated with atypical partner choice and lead to regret. Illegality ofmarijuana sometimes facilitated intimate encounters. Conclusions: Results can inform prevention efforts regarding specific sexual risks and allow us to design more realistic prevention programs and interventions to guide potential users to make safer choices. Financial support: This pilot study was funded by the Center for Drug Use and HIV Research (P30DA011041).

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