Abstract
Accurate radiation targeting of pancreatic cancer for stereotactic treatment allows for higher radiation doses in a shorter period of time, while limiting toxicity to nearby organ. EUS-guided fiducial placement of metal coils has been well described as a minimally invasive technique to localize pancreatic cancer for stereotactic body radiotherapy. A new injectable hydrogel made of iodinated polyethylene glycol particles has been approved and used as a liquid fiducial on solid tumors. It is reabsorbable, can be easily injected through small gauge needles, and has multimodal (cone beam, ultrasound, CT and MR imaging) visibility without image artifact. To date there has been no reports on the use of this injectable radiopaque hydrogel delivered by EUS-guidance into pancreatic cancer.
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