Abstract

Prostate cancer is the most common cancer amongst men worldwide and major cause of cancer death. Current treatments of primary prostate tumors are initially effective, however, 25% of the patients develop metastatic disease. Once the cancer has acquired resistance to Androgen Deprivation Therapy, Castration Resistant Prostate Cancer (CRPC) occurs. At this stage, highly aggressive prostate cancer cells may have spread throughout the body and can form incurable metastases.

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