Abstract
Results: Angiographic restenosis occured in 44/318 pts and 45/355 lesions (12.7%). BMS use (46% vs 21%, p<0.001) and diabetes (30% vs 11%, p<0.001) were more prevalent in pts with restenosis vs no restenosis. IVUS minimum lumen area (MLA) (5.5 [4.1, 6.8] mm2 vs 6.6 [5.2, 8.0] mm2, p<0.001), MSA (5.6 [4.2, 7.1] mm2 vs 6.8 [5.3, 8.3] mm2, p<0.001), and reference lumen area (6.8 [5.5, 9.4] mm2 vs 9.3 [7.3, 11.6] mm2, p<0.001) were smaller in restenotic vs non-restenotic lesions. The frequency of MSA <5.0 mm2 was 39% in restenosis vs 19% in non-restenosis (p=0.001) whereas MLA <5.0 mm2 was present in 42% of restenosis vs 21% of non-restenosis (p<0.001). By multivariable analysis diabetes, DES use, stent length, and MSA were independent predictors of angiographic restenosis (Table). Conclusions: IVUS MSA predicts angiographic restenosis after primary PCI in STEMI pts, similar to stable pts.
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