Abstract
To Editor.— Numerous studies have shown that cromolyn sodium is an effective antiasthmatic medicine when used prophylactically on a regular basis. Cromolyn inhibits degranulation of sensitized mast cells that occurs after exposure to specific antigens, and inhibits release of histamine and SRS-A. The manufacturers of cromolyn, and investigators, advise a starting dose of 20 mg (one capsule) four times a day by inhalation, for children 5 years old and over. 1 The manufacturers' brochures state that the dose for adults and children 5 and over is contents of one Aarane capsule inhaled four times daily at regular intervals.... Dykes 2 specifies minimum dosage that is found effective. For this reason, following case illustrates an important point. Report of a Case.— A 5-year-old white boy gave a three-year history of asthma, and had been wheezing almost daily for two years. His wheezing increased with exercise.
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More From: JAMA: The Journal of the American Medical Association
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