Abstract

This work proposes the miniaturization and modification of the QuEChERS strategy using different large pore mesostructured silicas, non-modified and modified with amino groups (NH2), as dispersive clean-up sorbents for multi-component extraction of 21 pyrrolizidine alkaloids from different aromatic herbs, combined with ultra-high performance liquid chromatography coupled to tandem mass spectrometry analysis. The procedure was miniaturized by reducing the amounts of sample (0.2 g), solvents (2 mL), clean-up sorbents (25 mg sorbent + 150 mg MgSO4) and partitioning salts (0.65 g) employed. Best results were achieved using mesostructured silicas (LP-MS-NH2) than conventional PSA. The method was validated (overall recoveries 73–105%) and applied to the analysis of 17 samples. All the samples were contaminated with PAs (average concentration 262 µg/Kg). Thyme and basil samples were the most contaminated, whereas rosemary was the least. Lasiocarpine, senecivernine N-oxide and europine N-oxide were the main PAs that contributed to their contamination.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.