Abstract

This review describes the importance of antifungal drugs in medicinal, pharmaceutical and agriculture fields because of their wide spectrum of biological activities in the recent years. Their chemical structure has expected considerable interest. Also, we focus on urinary problems and can be helpful to develop the ideas in neurological bladder for see the interactions and effect of antifungal drugs in system neurologic, because urinary tract infection is one of the most frequent diseases in medical practice. Some definitions are discussed and reported emphasizing microbiological, clinical and therapeutic aspects.

Highlights

  • The past decade has witnessed a significant increase in the prevalence of resistance to antibacterial and antifungal agents

  • The fact that the increase in the incidence of worldwide fungal infections and emergence of antifungal drug resistance which outcompetes the development of novel antifungal compounds, it becomes important to understand the various facets of infections and to understand the basic mechanisms that govern the development of resistance

  • This review focuses on some of the aspects of antifungals, their interactions between antifungal azoles and neurological bladder problems

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Summary

Introduction

The past decade has witnessed a significant increase in the prevalence of resistance to antibacterial and antifungal agents. The fact that the increase in the incidence of worldwide fungal infections and emergence of antifungal drug resistance which outcompetes the development of novel antifungal compounds, it becomes important to understand the various facets of infections and to understand the basic mechanisms that govern the development of resistance. This enforces the widening of the hunt for the development of new antifungals targeting novel pathways. This review focuses on some of the aspects of antifungals, their interactions between antifungal azoles and neurological bladder problems

Antifungal drugs and some urinary problem
Types of neurogenic bladder dysfunction
Biological activity of imidazoles
Antifungal and antibacterial activity
Anti-inflammatory and analgesic activities
Anti-tubercular activity
Anti-depressant activity
Anti-cancer activity
Anti- viral activity
Antileishmanial activity
Conclusions
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