Abstract
Analyses of human milk samples reveal that although folate binding protein (FBP) concentration varies considerably among individuals, a positive correlation with milk folate concentrations exists. The equation expressing this relationship is Y=29.2+0.78 X, where Y and X represent FBP and folate concentrations, respectively. Since folylpolglutamates comprise at least half of total milk folate and are known not to cross biological membranes, these data suggest that folate is likely to be secreted from the lactating cell as a complex with FBP. This complex could exit from the lactating cell by a route which is common to other milk proteins.
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