Mid term result of transcatheter thrombolysis for acute pulmonary embolism

Abstract

Objective Pulmonary embolism is a common cardiovascular emergency with the characteristics of high incidence, high mortality. This study compared pulmonary artery catheter thrombolysis with peripheral intravenous thrombolysis for acute pulmonary embolism in the mid-term clinical efficacy. Methods From June 2011 to September 2015, 68 patients were given pulmonary artery interventional therapy, 54 cases received peripheral intravenous thrombolysis; discharged patients were followed up for 3-12 months to evaluate the curative rate, effective rate, recurrence rate and the incidence of complications. Results Follow up rate was 79.5%. The cure rate of the treatment group was higher than that of the control group (47.3% vs 23.8%, P<0.05); The significant effective rate of the treatment group was higher than that of the control group(81.8% vs 52.4%, P<0.05); The incidence of Chronic pulmonary hypertension (1.8%) was lower than that of the control group (16.7%); There was no significant difference in improvement rate, recurrence rate and mortality. Conclusion The medium-term efficacy of pulmonary artery catheter directed thrombolysis is superior to that of peripheral intravenous thrombolysis; it can effectively reduce the incidence of chronic thromboembolic pulmonary hypertension. Key words: Pulmonary embolism; Mechanical thrombolysis; Interventional therapy