Abstract

A simple ecofriendly microwave supported solvent free synthesis of bis-chalcones was carried out by the reaction of di-substituted 4-hydroxy-3-methoxy benzaldehyde with different substituted N-phenylpiperidine-2,6-diones in presence of neutral corundum. By the same way the novel bis-pyrazoles were developed from bis-chalcones and hydrazine hydrate with neutral corundum. All the derivatives were characterized and screened their antimicrobial potencies.

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