Abstract
THE use of potassium permanganate as a biological fixative for revealing the membrane systems of cells is well known to electron microscopists1. This fixative has been successful in preserving the fine morphology of bacteria and yeast; but, up to date, workers have failed to show the true nature of the membranes in these organisms2,3. This communication describes a method for stabilizing and increasing the electron density of membranes in micro-organisms by post-fixiiig them with a uranium salt.
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