Abstract
A growing proportion of adolescents with type 1 diabetes mellitus (T1DM) are overweight or obese. Metformin appears to have some benefit in overweight/obese adults with T1DM, but data for adolescents are lacking. Investigators from 26 sites randomized 140 adolescents (mean age, 15.3 years; age range, 12–19.6 years; 66% female; 74% white) with presumed autoimmune T1DM (age <10 years at diagnosis or presence …
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