Abstract
Renal cell carcinoma (RCC) metastasis to the oral cavity is relatively rare. The oral manifestation of RCC is related to high rates of morbidity and worsening of the clinical prognosis. A 61-year-old male patient with a previous diagnosis of renal cancer was referred to the dental service with a complaint of nodular lesion in the oral cavity. On intraoral examination, an extensive nodular lesion on the gingiva associated with the upper molars was noted. After biopsy, the microscopic examination revealed nests of polygonal cells partitioned by fibrovascular septa in an alveolar arrangement. Immunohistochemical analysis showed positivity for AE1/AE3, PAX8, CD10, and vimentin markers. Tumor cells were negative for CD34 and CD163. The diagnosis of oral metastasis of RCC was made. The patient has been treated with chemotherapy and care monitoring by a multidisciplinary team.
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