Abstract
Article1 February 1956METACORTANDRACIN (METICORTEN) IN THE TREATMENT OF DISSEMINATED LUPUS ERYTHEMATOSUS AND PERIARTERITIS NODOSACHARLES LEROY STEINBERG, B.S., M.D., F.A.C.P., ANDRIES I. ROODENBURG, M.D., M.S. (Medicine)CHARLES LEROY STEINBERG, B.S., M.D., F.A.C.P.Search for more papers by this author, ANDRIES I. ROODENBURG, M.D., M.S. (Medicine)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-2-316 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDisappointment in the long-term treatment of rheumatic diseases with cortisone and allied steroids has stimulated a search for newer compounds. Two of these compounds are metacortandracin and metacortandralone, which were recently reported as being of value in the treatment of rheumatoid arthritis by Bunim et al.1They recently made preliminary observations on the antirheumatic and anti-inflammatory potency of these synthetic steroids. The structural formula of metacortandracin and metacortandralone and their close relationship to cortisone and hydrocortisone are noted in the figures below. Studies2indicated that these compounds possessed three times the activity of cortisone and twice the activity of hydrocortisone,...Bibliography1. BunimPechetBollet JJMMAJ: Preliminary observations on the antirheumatic potency, metabolic effects, and hormonal properties of metacortandralone and metacortandracin, Proceedings of the First Interim Scientific Session, Bethesda, Maryland, November 4, 1954. Google Scholar2. HerzogNobileTolksdorfCharneyHershbergPerlman HLASWEBPL: New anti-arthritic steroids, Science 121: 176, 1955. CrossrefMedlineGoogle Scholar3. Tumulty PA: The clinical course of systemic lupus erythematosus, J. A. M. A. 156: 947, 1954. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, N. Y.*Received for publication August 8, 1955.From the Arthritis Clinic, The Rochester General Hospital, Rochester, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byProphylaxis in patients receiving adrenal steroid therapyMyocardial infarction following steroid therapy in periarteritis nodosaDas adrenocorticotrope Hormon (ACTH), die HormonederNebenniere(Cortison,Adrenalin) das Insulin, sowie die Hormone der Schilddrüse und NebenschilddrüseMyokarditis und weitere MyokardiopathienKrankheiten der GefäßeSTEROID THERAPY IN COLLAGEN DISEASES. *Periarteriitis nodosaDer viscerale Lupus erythematosus (Kaposi-Libman-Sacks-Syndrom) 1 February 1956Volume 44, Issue 2Page: 316-336KeywordsHospitalsLupus erythematosusPediatricsPhotographyRheumatic feverRheumatoid arthritisSteroids ePublished: 1 December 2008 Issue Published: 1 February 1956 PDF downloadLoading ...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
