Abstract

Background and Aims : Non-alcoholic fatty liver disease (NAFLD) is the most frequent cause of chronic liver disease in the western world. Steatosis can be accompanied by inflammation and cell damage (non-alcoholic steatohepatitis, NASH) as well as fibrosis. Sphingolipids and in particular an atypical class of 1-deoxysphingolipids have been associated with NAFLD. Increased 1-deoxySL formation is typically related to an altered amino acid homeostasis. We therefore analyzed the metabolic background that is associated with the increased formation of these lipids in NAFLD.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.