Abstract
Eels were injected intraperitoneally with insulin (100 IU/kg) and during 14 days the effects on different metabolites in blood, liver and muscle were studied. Exogenous insulin had a marked effect on carbohydrate metabolism. The observed changes (hypoglycemia, depletion of hepatic glycogen and an initial increase in muscle glycogen formation) indicate that insulin in eels induces effects on carbohydrate metabolism qualitatively similar to those found in mammals. Insulin also appears to have an important function in the regulation of lipid metabolism in eels, indicated by a rapid decrease in plasma FFA and a somewhat delayed decrease in other blood lipids. Protein metabolism and plasma inorganic ions were only slightly affected after insulin injection.
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