Abstract

Heart disease is a major cause of health problems worldwide. There are many different types of heart disease, but one that is fairly common and can have lots of negative side effects is called cardiomyopathy. We know that humans and many mammals, including dogs, get cardiomyopathy. In dilated cardiomyopathy the heart changes shape and often the electrical signals within the heart change. Because of these changes, the heart is not able to pump blood around the body very well, which means that oxygen and nutrients are not delivered to the body at the optimal levels. This can affect day-to-day life, and it can also cause early death. Understanding cardiomyopathy and finding the mutations in genes that cause it are essential, as this information can help us to diagnose, treat, and prevent this heart disorder. We can try to mend the broken hearts that do not work properly. In dogs with cardiomyopathy, we have discovered genetic mutations and found links between these changes in the dogs’ hearts.

Highlights

  • Heart disease is a major cause of health problems worldwide

  • There is a heart disorder that is referred to a “broken heart syndrome”— called takotsubo or stress cardiomyopathy

  • Extreme sudden happiness, and even stress can cause this problem. It is one of several different types of “cardiomyopathy,” heart disorders that are seen in humans and animals

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Summary

THE HEART

The heart pumps blood to the lungs where oxygen goes into the blood, it is pumped back to the heart and this blood gets pumped around kids.frontiersin.org. The famous Greek philosopher Aristotle, born 2,402 years ago, said the heart was the most important organ of the body. Plato, another philosopher, and Hippocrates, a great doctor, worked in the same era as Aristotle and they noticed that the heart was important for pumping blood around the body. The heart has become a very important symbol of emotions throughout history, in cultures and religions across the world. It is a symbol of love, a place where the soul might live and where emotions and reason come from. How many times a day do we see it as an emoji? Throughout time and in every part of the world, the heart is a necessary organ and helps us show emotion

HOW DO HEARTS GET BROKEN?
THE HIDDEN CODE BEHIND HEART DISEASE
WHAT IS THE DNA CODE?
SEARCHING FOR MUTATIONS IN DOGS WITH CARDIOMYOPATHY
RESTRICTIONFRAGMENT GENOTYPING
THE FUTURE
Findings
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