Abstract

I would like to reemphasize that MDMP is different than pulse methylprednisolone and conventional corticosteroid administration as was used for D-B anemia [5,6] long period as advised. In conventional corticosteroid treatment 1-2 mg/kg/day dose in gven 6-8 or 12 hours intervals. In pulse methyprednisolone treatment 1 g methlyprednisolone (MP) is giving i.v within 4 hours, at any time of the day. In MDMP treatment, methylprednisolone MP initial dose 30-100 mg/kg day is given within 10 to 15 minutes IV or at once orally arouned 6 am, 3 days then 20-50 mg/ kg, day for 4 days subsquently 10,5,2,1 mg/kg dose given for 1 week each according to response).

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