Abstract
Patients and physicians confront a challenging dynamic when an early pregnancy loss (EPL) occurs after fertility treatment (FT). Our study focused on the time to resumption of FT in patients managed medically (Cytotec) compared to in those managed surgically with dilatation and curettage (DC p = 0.01). More D&C patients received karyotype results (68% vs 5%). A significant difference was not found in resumption time to the next fertility treatment between the medically and surgical treatment. More medically managed patients RPOC requiring D&C. Although a D&C is more likely to provide karyotype results, medical management is a viable alternative.
Highlights
Patients who undergo fertility treatment cope with a challenging process in trying to conceive a healthy off-spring
Our study focused on the time to resumption of fertility treatment (FT) in patients managed medically (Cytotec) compared to in those managed surgically with dilatation and curettage (D & C)
In an effort to better counsel patients that could empower them to make the best decision for their specific case and to establish a “best practice” in the management of EPL in an infertility population, we investigated whether surgical or medical management of an early pregnancy loss led to the more rapid resumption of infertility treatment
Summary
Patients who undergo fertility treatment cope with a challenging process in trying to conceive a healthy off-spring. The emotional and psychological duress is further compounded in cases that result in an early pregnancy loss (EPL). EPL is defined by the sum of both biochemical pregnancy (the loss of concept us after the first measurement of βhCG level but before the ultrasound (US) confirmation of implantation) and early clinical miscarriage (the confirmation of a pregnancy loss after US confirmation of a viable pregnancy and before the beginning of the second trimester) [1]. Miscarriage is the most common gynecological emergency Additional risk factors include smoking and poor quality embryos, which double and triple the risk of a miscarriage respectively [6]
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