Mediating and modulating effects of self-efficacy between health literacy and quality of life in patients with esophagus cancer receiving chemotherapy

Abstract

Objective To analyze the mediating and modulating effects of self-efficacy between literacy and quality of life in patients with esophagus cancer receiving chemotherapy. Methods Totally 105 patients receiving chemotherapy for esophagus cancer in Heping Hospital Affiliated to Changzhi Medical University from January 2015 to December 2017 were selected by convenient sampling and investigated with General Self Efficacy Scale (GSES) , Health Literacy Management Scale (HeLMS) and Spitzer Quality of Life Index (SQLI) . Pearson correlation analysis was used to analyze the correlation between the patients' self-efficacy, literacy and quality of life, and regression analysis was used to mediating and modulating effects between the variables. Results The average self-efficacy score, literacy score and quality of life score of the 105 patients were (2.38±0.47) , (86.65±12.29) and (4.94±0.55) , respectively. Pearson correlation analysis showed that self-efficacy was positively correlated with literacy and quality of life (r=0.517, 0.462; P<0.05) . Self-efficacy showed mediating effects between literacy and quality of life in the patients with esophagus cancer, which accounted for 34.82% in the total effect. Regression analysis showed that the regression coefficient of the interacting health literacy×self-efficacy was statistically significant (β'=0.015, t=2.718; P<0.01) , whose mediating effect was significant (ΔR2=0.018, P<0.01) . Conclusions Self-efficacy has mediating and modulating effects between literacy and quality of life in patients receiving chemotherapy for esophagus cancer. Key words: Esophagus neoplasms; Quality of Life; Self-efficacy; Health literacy; Mediating effect; Modulating effect; Chemotherapy