Abstract
Diabetes leads to end-stage renal disease in a considerable fraction of patients. A number of risk factors for this process can be identified. These include glycemic control, familial and ethnic risks, and hemodynamic alterations in both systemic and intrarenal hypertension. This latter category of hemodynamic risks may interact with metabolic and genetic influences to ultimately produce progressive diabetic nephropathy. However, manipulation of these vascular stresses by antihypertensive therapy presently offers the most efficacious means of influencing the progression and perhaps even clinical appearance of diabetic nephropathy.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
