MECHANISMS OF CHROMOSOME BANDING AND IMPLICATIONS FOR CHROMOSOME STRUCTURE

Abstract

INTRODUCTION 25 HlSTONES AND CHROMOSOME BANDING .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 C-BANDING-EXTRACTION OF NON-C-BAND DNA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 G-BANDS=CHROMOMERES OF MEIOTIC CHROMOSOMES 29 MAJOR G-BANDS ARE COMPOSED OF SEVERAL SMALLER CHROMOMERES .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 GIEMSA STAINING-SIDE STACKING OF THIAZIN DYES ON DNA ..... . . . 30 G-BANDING-ENHANCEMENT OF THE CHROMOMERE PATTERN ... . . . . . 3 1 Q-BANDING-DETECTION OF AT-RICH DNA .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 HOECHST 33258 BANDING-DETECTION OF AT-RICH DNA ... . . . . . . . . . . . . . . . . . . . 35 R-BANDING DETECTION OF GC-RICH DNA 35 Qor R-BANDING BASED ON EARLY REPLICATING DNA IN R-BANDS AND LATE REPLICATING DNA IN Qor G-BANDS . . . . . . . . . . . . . . . . . . . . . . 37 CHROMOSOME BANDS DELINEATE THREE TYPES OF CHROMATIN .... 38 IMPLICATION OF CHROMOSOME BANDING FOR CHROMOSOME STRUCTURE 39