Abstract
Growth hormone releasing hormone (GHRH) and somatostatin (SRIF) are secreted by the hypothalamus. After traversing the hypophyseal portal system, these two peptides will bind to their respective receptors situated on the somatotroph cells. Nevertheless, regulation of pituitary growth hormone (GH) secretion is mediated by several hormonal and central nervous system signals. GH is secreted in a wave-like pulsatile fashion. The pattern of GH secretion is considered in more detail elsewhere in this volume. GHRH and SRIF act out of phase to stimulate or suppress GH secretion, respectively. Peripheral hormones, including steroid and thyroid hormones as well as insulin-like growth factor I (IGF-I) and insulin-like growth factor II (IGF-II), also participate in the control of GH secretion.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
