Abstract

Endometriosis is a multifactorial disease with pathophysiological factors not yet well known; it also presents a wide symptomatic range that makes us think about the need for multidisciplinary management. It is a chronic disease in which there is no definitive treatment, and is associated in a large majority of cases with psychological pathology. Connecting comorbidities and multimorbidities on a neurobiological, neuropsychological, and pathophysiological level could significantly contribute to their more successful prevention and treatment. In our study, resilience is analyzed as an adjunctive measure in the management of endometriosis. Methods: A multi-centre, cross-sectional study was performed to analyse resilience levels in a sample of Spanish women suffering from endometriosis. CDRIS-25, CDRIS-10, BDI, the STAI, and the SF-36 Health Questionnaire were used for assessments. A representative group of 202 women with endometriosis was recruited by consecutive sampling. Exploratory and confirmatory factor analyses were performed for both resilience scales. Results: Mean CDRIS-25 and CDRIS-10 scores were 69.58 (SD 15.1) and 29.37 (SD 7.2), respectively. Women with adenomyosis and without signs of deep endometriosis showed the lowest scores. The best predictive model included women’s age, years of endometriosis evolution, number of pregnancies, and history of fertility problems as the best predictive factors. Conclusions: Women build resilience as the number of years of evolution of the disease increases. Symptoms such as dyspareunia and continued abdominal pain were more prevalent among less resilient women.

Highlights

  • Endometriosis is a condition defined as a benign and proliferative disorder characterized by the ectopic presence and growth of functional endometrial tissue, glands, and stroma outside the uterine cavity [1]

  • Between 1 January and 30 June 2021, a multi-centre, cross-sectional study was performed to analyse resilience levels in a sample of Spanish women suffering from endometriosis

  • Several scales can be used, such as the CDRISC-10 and CDRISC-25, which have been validated in women with endometriosis

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Summary

Introduction

Endometriosis is a condition defined as a benign and proliferative disorder characterized by the ectopic presence and growth of functional endometrial tissue, glands, and stroma outside the uterine cavity [1]. It is a chronic inflammatory disease and one of the most common gynaecological issues. As endometriosis may have a subclinical course, the real prevalence may be underestimated. It has been reported in up to 50% of women suffering from infertility [4]. The clinical features of endometriosis are variable and unpredictable in both presentation and course. Affected women usually present with pain and infertility during their reproductive years [5,6]

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