Abstract
Three magnetic susceptibility meters forin vivo measurements of hepatic iron were built based on the same principle as that ofBauman andHoffman (1967). One system used Invar in the magnetic path, one used ferrite, and the third used air. Systems with ferromagnetic cores suffer from a highly inhomogeneous field. The system without ferromagnetic cores showed a considerable improvement in this respect. The temperature instability of the devices with ferromagnetic cores could be reduced by using heat shields between the specimen and the cores. Thus the temperature sensitive ferrite cores could be used instead of the expensive Invar cores. The sensitivity of the instruments is insufficient to show iron deficiency (anaemia) in the living rat (iron concentration less than 0·25 mg/g), but an overload of four times the normal concentration is significantly detectable.
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