Abstract
Tissues that do physical and/or chemical work, such as heart, kidney, and skeletal muscle, exhibit a close relationship between energy metabolism and the level of functional activity. The existence of a similar relationship in the tissues of the central nervous system has been more difficult to prove, partly because of uncertainty about the nature of the work associated with nervous functional activity but mainly because of the difficulty in assessing the levels of functional and metabolic activities in the same functional component of the brain at the same time.
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