Abstract
Vitamin D [ergocalciferol (D2) and cholocalciferol (D3)] is 25-hydroxylated by the liver and subsequently hydroxylated by the kidney to form 1,25-vitamin D, the active form of the vitamin. 25-Hydroxyvitamin D (25-OH-vitamin D) and 1,25-dihydroxyvitamin D have important effects on calcium absorption, bone calcium balance, and renal excretion of calcium and phosphorus (1). Assessment of the monohydroxy form of vitamin D is important for identifying insufficient endogenous synthesis disorders that impair gastrointestinal absorption and to identify renal or hepatic abnormalities (2). Here we report on 25-OH-vitamin D as measured by the Nichols ADVANTAGE® 25-OH Vitamin D, DiaSorin LIAISON® 25-OH Vitamin D, DiaSorin 25-OH Vitamin D RIA, …
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