Abstract

Carotid artery stenting (CAS) patients enrolled in the Nanjing Stroke Registry between December 2005 and November 2016. There were 261 patients underwent CAS and digital subtraction angiography, computed tomographic angiography, or duplex ultrasonography 6 months and annually after the procedure. Aspirin and clopidogrel were administered before and after CAS in all patients. Forty-six (17.6%) patients developed recurrent stenosis (> 50% luminal diameter reduction) during a mean follow-up of approximately 1 year. On multivariate analysis, baseline mean platelet volume (MPV) >10.1 fL, lesion length, residual stenosis, and baseline glucose were associated with recurrent stenosis. Patients with MPV >10.1 fL were three times more likely to develop recurrent stenosis after CAS than patients with lower MPVs. Patients with high MPV may benefit from intensified antiplatelet therapy after CAS.

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