Abstract
Primary hyperparathyroidism creates a multisystem and life-limiting disease burden requiring early recognition to mitigate potential complications. A single parathyroid adenoma is responsible for 80% to 85% of primary hyperparathyroidism, causing subjective cognitive impairment, neuropsychiatric symptoms, osteoporosis-associated bone/joint pain, renal damage, functionality, and poor quality of life. The benefits of treatment include clinically significant fracture risk reduction, improvement in left ventricular hypertrophy, and frailty indices. The criteria for parathyroidectomy to resolve primary hyperparathyroidism are less clear for those over age 85. Evidence-based screening tools are available for advanced practice nurses to quantify the associated risk of complications and poor outcomes.
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