Maternal iron and zinc and preterm labor risk: A nested case-control study based on the Lanzhou Birth Cohort Study (BBCS) in China.
The aim of this study was to investigate the effect of dietary iron and zinc in-take on the risk of preterm labor before and during different trimesters, and to assess whether there is an interaction between iron and zinc intake and the risk of preterm labor. The study was a nested case-control study of 880 cases and 8017 controls in Lanzhou City, northwest China. Unconditional logistic regression was used to determine the association between dietary iron/zinc intake and the risk of preterm labor and its clinical subtypes. Multivariable-adjusted restricted cubic spline (RCS) modeling was used to explore the non-linear relationship between dietary iron/zinc intake levels and the risk of preterm birth. Lower iron/zinc intake before and during pregnancy was associated with a higher risk of preterm labor and some of its subtypes, and there was a non-linear trend between iron/zinc intake and risk of preterm labor (p non-linear <0.05). A synergistic effect of low iron and zinc intake on the risk of preterm labor was also observed. We observed a significant increase in the risk of preterm labor in women with low dietary zinc intake before and during pregnancy, with a dose-response relationship. Similarly, there was a significant negative association between lower dietary iron intake during pregnancy and preterm labor. In addition, there was a multiplicative interaction between low dietary iron and zinc intake and preterm delivery before pregnancy and during three different periods of pregnancy. Higher dietary intake of iron and zinc before and during pregnancy may reduce the risk of preterm labor. Low intakes of iron and zinc during pregnancy appear to have a synergistic effect on the risk of preterm labor.
- Research Article
82
- 10.1016/j.jad.2011.09.039
- Oct 24, 2011
- Journal of Affective Disorders
Low dietary or supplemental zinc is associated with depression symptoms among women, but not men, in a population-based epidemiological survey
- Research Article
- 10.1016/s0002-8223(98)00459-3
- Sep 1, 1998
- Journal of the American Dietetic Association
Dietary Zinc Intake and Urinary Zinc Excretion in Diabetic Nephropathy
- Research Article
1
- 10.33633/visikes.v11i1.663
- Apr 26, 2012
- Visikes: Jurnal Kesehatan Masyarakat
Background : Severe malnutrition was threatening children under five years growth. Protein deficiency in long time caused severe malnutrition. Children with severe malnutrition had micronutrients deficiency, like iron and zinc. Iron and zinc deficiency caused nutritional status decreasing. Objective : This research conduct to analyze the association dietary protein, iron, and zinc intake with nutritional status in severe malnutrition children under five years of age. Method : Study cross sectional in 21 severe malnutrition children under five years of age at work region Semarang City Health Department.The data nutritional status were searched using indicator of weight by height (W/H). The data dietary protein, iron, zinc, and fiber intake were searched by semi quantitative food frequency questionnaire (SQFFQ). The data analyzed by SPSS 12.0 for windows. Bivariate analysis used pearson product moment and multivariate analysis used multiple regression linier. Result : Nutritional status subjects which using W/H indicator were -5.72 until -3.02. At 13 until 36 month of age, subjects had 6.8 gr/d until 31.5 gr/d dietary protein intake, 1.3 mg/d until 6 mg/d dietary iron intake, and 1 mg/d until 3.3 mg/d dietary zinc intake. At 37 until 59 month of age, subjects had 11.3 gr/d until 48.5 gr/d dietary protein intake, 2.6 mg/d until 10.2 mg/d dietary iron intake, and 1.5 mg/d until 5.6 mg/d dietary zinc intake. Most of dietary protein (61.9%), iron (90.5%), and zinc (100%) intake were deficit category according to Recommended Dietary Allowances. But, most of dietary protein (61.9%) and zinc (57.1%) were good category, and all of dietary iron was deficit category according to each dietary requirements. There were no association between dietary protein (r=0.143;p=0.27), iron (r=0.089;p=0.35), and zinc intake (r=0.122;p=0.3) with nutritional status in severe malnutrition children under five years of age. Conclusion : There were not evidenced of association between dietary protein, iron, and zinc intake with nutritional status in severe malnutrition children under five years of age. Keywords : Nutritional status, severe malnutrition children under five years of age, protein intake, iron intake, and zinc intake
- Research Article
14
- 10.1186/s40795-018-0237-8
- Aug 9, 2018
- BMC nutrition
BackgroundAdequate zinc intake is essential for the growth and neurobehavioral development of young children. Zinc deficiency in children is recognized as risk factor for stunting. In Ethiopia, 38% of children under five years of age are stunted. This analysis was conducted to measure dietary zinc intake and to identify its determinants among children 6–35 months of age to design appropriate intervention.MethodsNationally and regionally representative data available from 6752 children 6–35 months of age from the Ethiopian national food consumption survey were analyzed. A multivariate model was used to identify determinants of dietary zinc intake.ResultsWe found low dietary zinc intake among children 6–35 month age. National average dietary zinc intake was 1.74 mg/day. Socio-economic status, maternal education, and maternal age were positively associated with dietary zinc intake, while the number of children under 5 years-of-age in a household was negatively associated with dietary zinc intake (p < 0.0001). Children reportedly sick in the previous 2 weeks were most likely to have low dietary zinc intake (p < 0.0001).ConclusionThe observed low dietary zinc intake in Ethiopian children has a significant association with health status of children, providing evidence for nutrition and health planners to emphasize on promoting consumption of zinc rich foods and preventing morbidity from common infections.
- Research Article
- 10.1016/s0924-9338(13)77391-7
- Jan 1, 2013
- European Psychiatry
2803 – Dietary Zinc Intake and the Risk of Depression in Middle-Aged Men: A 20-Year Prospective Follow-Up Study
- Research Article
33
- 10.1016/s0002-8223(97)00304-0
- Nov 1, 1997
- Journal of the American Dietetic Association
Plasma and Erythrocyte Zinc Concentrations and their Relationship to Dietary Zinc Intake and Zinc Supplementation During Pregnancy in Low-Income African-American Women
- Research Article
38
- 10.1016/j.clnu.2020.07.005
- Jul 15, 2020
- Clinical Nutrition
Dietary zinc intake and incident chronic kidney disease
- Research Article
38
- 10.1016/j.jad.2013.03.027
- May 2, 2013
- Journal of Affective Disorders
Dietary zinc intake and the risk of depression in middle-aged men: A 20-year prospective follow-up study
- Supplementary Content
- 10.1016/s0141-7037(95)80038-7
- Jan 1, 1995
- Journal of the British Contact Lens Association
Publication guidelines and instructions to authors
- Research Article
11
- 10.1007/s12011-023-03563-w
- Feb 7, 2023
- Biological Trace Element Research
This study assessed the independent association of dietary selenium and zinc intakes with the risk of hypothyroidism and interaction effect between dietary selenium and zinc intakes with the risk of hypothyroidism in Americans. The data of this cross-sectional study was from the National Health and Nutritional Examination Survey (NHANES) 2007-2012. The outcome was defined as new-onset hypothyroidism. Weighted univariate and multivariate logistic regression and the subgroup analyses based on gender and body mass index (BMI) were conducted to evaluate the association between the dietary selenium and zinc intakes and new-onset hypothyroidism. Odds ratio (OR) and 95% confidence interval (CI) were calculated. A total of 6402 participants were included with 131 (2.05%) developed a hypothyroidism in this study. Compared with participants with high zinc intake, those with low zinc intake had a higher risk of new-onset hypothyroidism (OR = 1.74, 95% CI: 1.05-2.90). Moreover, we also found a significant interaction between dietary selenium level intake and dietary zinc level intake on new-onset hypothyroidism risk (OR = 5.99, 95% CI: 1.77-20.23). There was an interaction between dietary selenium and zinc intakes on the risk of new-onset hypothyroidism, especially the significant effect for adults with women or overweight. The findings indicated that improving the levels of dietary zinc and selenium intake may be beneficial in preventing of new-onset hypothyroidism.
- Discussion
3
- 10.1016/s0140-6736(13)61975-3
- Dec 1, 2013
- The Lancet
Child labour must be on the post-2015 agenda
- Research Article
7
- 10.1016/j.clnesp.2020.12.030
- Feb 12, 2021
- Clinical Nutrition ESPEN
Causal effects of dietary calcium, zinc and iron intakes on coronary artery disease in men: G-estimation and inverse probability of treatment weighting (IPTW) analyses.
- Research Article
7
- 10.1007/s11845-022-03181-w
- Oct 12, 2022
- Irish Journal of Medical Science
BackgroundIn humans, zinc is involved in many biological functions acting as signaling ion, neurotransmitter, structural component of proteins, and cofactor for many enzymes and, through this, is an important regulator of the immune and nervous system. Food supplies zinc to the human body, but a high prevalence of inadequate dietary zinc intake has been reported worldwide.AimsThe objective of this study was to investigate the zinc intake and bioavailability of over 250 women (pregnant and non-pregnant) based in Ireland, in order to evaluate the dietary inadequacy of zinc.MethodologyWe used a food frequency questionnaire designed to assess the zinc intake and bioavailability of the participants.ResultsOur results show that 58% of participants are at risk of inadequate zinc intake and that 29% may be zinc deficient. The prevalence of inadequate zinc intake was lower for pregnant women (zinc deficient 9%, at risk 38%) than for non-pregnant women due to more frequent consumption of supplements. Low zinc intake was not correlated with the age of participants and resulted from a combination of inadequate intake of zinc-rich food and relatively higher intake of food items rich in phytate, a major zinc uptake inhibitor.ConclusionsWe conclude that at present, low zinc intake may be prevalent in as much as 87% of women, including 47% of pregnant women. Therefore, zinc status needs to be considered as a factor impacting the health of women, and in particular pregnant women, also in industrialized and developed countries such as Ireland.Supplementary InformationThe online version contains supplementary material available at 10.1007/s11845-022-03181-w.
- Research Article
122
- 10.1016/j.psychres.2017.02.006
- Feb 3, 2017
- Psychiatry Research
Dietary zinc and iron intake and risk of depression: A meta-analysis
- Research Article
6
- 10.6133/apjcn.202112_30(4).0017
- Dec 1, 2021
- Asia Pacific journal of clinical nutrition
The differences of dietary iron and zinc intakes between patients with nonalcoholic fatty liver disease (NAFLD) and controls remain controversial. The meta-analysis aimed to explore the differences of dietary iron and zinc intakes between NAFLD patients and healthy subjects. A systematic literature search was performed up to July 2021 in databases of PubMed, Embase, Web of Science, Cochrane Library, Chinese National Knowledge Infrastructure (CNKI), and Wanfang. Using a randomeffects model, the differences of dietary iron and zinc intakes between cases and controls were calculated as standardized mean differences (SMDs) with 95% confidence intervals (CIs). A total of 21 studies from 19 articles with 6639 cases were included. The pooled estimate showed no difference in dietary iron consumption in the NAFLD groups compared with control groups. The difference became significant in Asia (SMD=0.16; 95% CI: 0.04, 0.28; I2=89.1%; pheterogeneity<0.001) as well as in cross-sectional studies (SMD=0.12; 95% CI: 0.07, 0.17; I2=4.7%; pheterogeneity=0.350). The difference in dietary zinc intake between cases and controls was not significant. We noticed a statistically significant increase of dietary zinc intake in NAFLD compared to controls in studies using food-frequency questionnaire (FFQ) to evaluate dietary intake (SMD=0.15; 95% CI: 0.10, 0.20; I2=12.2%; pheterogeneity=0.332). Our findings indicated that dietary iron intake in patients with NAFLD was higher than healthy subjects in Asia.
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