Abstract

Abstract A case of a 38‐year‐old woman with a mastocytosis syndrome is presented. The urinary excretion of histamine, methylhistamine and 1‐methyl‐4‐imidazole acetic acid was considerably higher than normally. Treatment with l‐hyoscyamine sulphate abolished gastritis, diarrhoea and pressure‐induced pain, and reduced dermographism and itching. However, there was no effect on the abnormal urinary histamine excretion.

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